Most of the exons and exon-intron boundaries of FⅪ gene of proband were examined by PCR and sequencing. The family people had been tested when it comes to mutant website of proband. Then the mRNA of FⅪ in the proband had been examined with RT-PCR. Results The proband-1 was a 7-year-old child, PT ended up being 10.7 s and APTT had been 97.4 s (reference range 9-12.8 s; 24-40 s), FⅪ∶C (0.6%) and FⅪ∶AgT (p.Gln263X) might be the molecular pathogenesis for just two probands with genetic coagulation factor Ⅺ deficiency. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective to evaluate the staging, restaging, and therapy strategy dedication of extranodal NK/T cellular lymphoma (ENKT) by PET/CT genuine body (true whole-body, TWB) imaging, which can be more advanced than PET/CT limitation of the entire body (restricted whole-body, LWB, from head vertex to upper thighs) by the addition of ‘distal reduced extremity’ images. Practices TWB 18F-FDG PET/CT studies carried out for staging and followup of ENKTL patients between January 2012 and September 2017 had been retrospectively reviewed. Patients in staging group got TWB PET/CT assessment for staging during the first analysis. In follow-up group, customers received follow-up evalution with TWB PET/CT and modern illness (PD) when you look at the LWB range with or without medical analysis or suspicion before follow-up examination, and then divided in to four subgroups staging (+) PD (－), staging (+) PD (+), staging (－) PD (－), staging (－) PD (+). Then portion of unforeseen ENKTL lesions bought at the distal extremity (outside the LWB range) (P1), therefore the per cent the initial diagnosis of TWB PET/CT staging, LWB PET/CT from the top of your head to the middle regarding the thigh is advised for routine follow-up. For ENKTL patients, TWB PET/CT was not carried out during the preliminary stage of diagnosis to detect the health of lower limbs. If the proof cyst progression into the LWB range showed up before the follow-up examination, TWB PET/CT had been suitable for the follow-up assessment to gauge the systemic tumor participation. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective To present our institutional expertise in laparoscopic spleen-preserving distal pancreatectomy (Lap-SPDP) using Kimura strategy with or without very early occlusion associated with foot of the splenic artery. In addition, to explore the safety and feasibility of the occlusion method, especially its benefits in intraoperative hemorrhage control and spleen preservation. Practices From February 2011 to May 2019, 54 successive customers who were identified as benign or low-grade malignant space-occupying lesions at the human anatomy additionally the end of pancreas underwent Lap-SPDP utilizing Kimura method within our institution. Twenty-five patients check details before 2015 had been allocated into non-occlusion team and 29 customers after 2015 were allocated into occlusion team. The non-occlusion team underwent direct dissection for the distal pancreas with blood circulation through the splenic artery also traditional traction of the splenic artery without occlusion. Whereas the occlusion team underwent short-term occlusion of this base of the Primary B cell immunodeficiency spleniood reduction (median, 100 mL vs. 200 mL) ( P0.05). Throughout the follow-up period (median (Min-Max), 13.5 (3-96) months), no perioperative death, infection recurrence, portal vein or splenic vein thrombosis, gastric varices or top intestinal bleeding was mentioned. Conclusion Lap-SPDP utilizing Kimura technique with very early health care associated infections occlusion regarding the cause of splenic artery was safe and feasible and could be generally speaking applied. By using this technique, we could reduce steadily the procedure some time loss of blood, in addition to sustain a high probability of spleen conservation. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective To investigate the heterogeneity for the developmental trajectory of posttraumatic anxiety disorder symptoms (PTS) among children and adolescents after Lushan quake also to explore the effect of sex and age from the trajectory. Techniques A total of 1 623 participants finished three tests at 14 days, a few months and six months after the earthquake. Latent growth mixture model (LGMM) ended up being used for statistical evaluation when you look at the computer software Mplus 8.0. Results The PTS developmental trajectories among children and adolescents confronted with the quake had four groups the conventional tension team (31.1%, course 1), the persistent disability team (4.5%, class 2), the psychological recovery group (46.8%, class 3) therefore the persistent mild symptom team (17.6%, class 4). The PTS development trajectories had been notably various in two sex teams, in addition to proportion of girls into the persistently hurt group ended up being greater than various other three teams. The PTS development trajectories had no difference between two age groups. Conclusion The developmental trajectories of PTS in kids and adolescents after the quake have considerable population heterogeneity, that will be affected by sex. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective to evaluate the connection between community personal capital and standard of living one of the middle-aged and elderly rural-to-urban residents, also to offer the policy guide for enhancing the wellness status.